We study the different mechanisms which make a specialized artery subtype known as the collateral artery. Collateral arteries bridge conventional arteries and establish connections between two distinct arterial trees. They receive blood flow from two directions when present naturally, but act as natural bypasses in the case of primary artery occlusions. These vessels are present in the heart and brain and serve as vital conduits that increase survival rates during heart attacks or strokes. The processes underlying collateral development and formation are the subject of numerous hypotheses. To address them, we employ a diverse range of cell and molecular biology techniques such as mouse genetics, experimental injury models, whole-organ and live imaging, transcriptomics, as well as in vitro and in vivo functional assays. Using this approach, we hope to unravel the complexities of collateral artery development and understand its contribution to tissue regeneration.
Swarnadip receives Best Oral Poster Presentation Award at the 47th All India Cell Biology Conference & International Symposium on 'Cell in Action' held at NISER, Bhubaneshwar
Opportunities
We are always looking for enthusiastic students and postdocs with an interest to explore different aspects of vascular biology in the context of development and disease. Please write to soumyashree at ncbs dot res dot in and tell us more about what excites you the most!
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